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Long-acting medications like semaglutide and tirzepatide tend to report higher rates of both diarrhea and constipation compared to short-acting options like exenatide

This vicious cycle of mtDNA damage accumulation and mitochondrial dysfunction further accelerates neurodegeneration and disease progression

Time and medical management allow the medication's effects to wear off naturally

It helps the body produce insulin more effectively and controls blood sugar levels while also reducing appetite, often leading to weight loss

Herbal medicines: report suspected adverse reactions to the Yellow Card Scheme

As semaglutide and tirzepatide seek to expand their approved indications, e.g., potentially adding heart failure, chronic kidney disease or MASH, following several successful phase 3 trial readouts in 2023 and 2024, more pathways open up to Medicare reimbursement of AOMs within existing rules